Systematic reviews and clinical trials on General Wellness sourced directly from PubMed (NCBI).
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2+ peer-reviewed studies in this area (2010–2025)
Recent systematic reviews & clinical trials
PubMed · 2023
Efficacy of vitamin D(3) supplementation on cancer mortality: Systematic review and individual patient data meta-analysis of randomised controlled trials
Kuznia S, Zhu A, Akutsu T et al. · Ageing research reviews
Personalization matters: the effect of sex in multivitamin-multimineral-based cancer prevention
Šelb J, Cvetko F, Deutsch L et al. · GeroScience
The prevention of non-communicable diseases like cancer contributes to healthy aging. Dietary supplements might support such prevention; their effect likely depends on the personal characteristics of the individuals receiving them. To evaluate the influence of sex on reducing cancer incidence with multivitamin-multimineral (MVM) supplementation, sex-specific results of the efficacy of MVM supplementation for cancer prevention were collected and meta-analyzed (using fixed effect (FE) and random effect (RE) models). Three trials included in the "US Preventive Services Task Force Recommendation Statement Report regarding Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer" were used, namely, COSMOS, SU.VI.MAX, and PHS2. A total of 28,558 men and 20,542 women were included. Multivitamin-multimineral supplementation significantly reduced cancer incidence in the entire population (HR 0.93 [95% CI, 0.88-0.99], FE and RE); sex-specific meta-analysis showed beneficial effects of supplementation in men (HR 0.91 [95% CI, 0.85-0.97] (FE)/0.88 [95% CI, 0.77-1.01] (RE)); however, there was no effect in women (HR 1.00 [95% CI, 0.88-1.14], FR and RE); (P
Source: All citations are sourced from PubMed (NCBI), the U.S. National Library of Medicine's database of peer-reviewed biomedical literature. Results are filtered to systematic reviews and clinical trials published 2015–2025.
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